Division of Molecular Cell Biology and Glycobiotechnology

Division of Molecular Cell Biology and Glycobiotechnology

Our main research focus is on the characterisation of the biological roles of posttranslational protein modifications and the molecular pathways involved in their generation. Particular emphasis is placed on protein glycosylation and the function of glycans in different cellular processes ranging from protein quality control to plant cell wall biosynthesis and control of plant growth.

Research in our division also includes the identification of intracellular protein trafficking routes in the secretory pathway of specialized tissues as well as the elucidation of the mechanisms governing proteolytic processing events in cells and organisms.

In the context of optimizing plant-based expression systems, another interest is the engineering of glycosylation pathways towards the production of well-defined homogeneous glycoforms on therapeutically relevant glycoproteins. Genetic modification of crop plants is used for the nutritional improvement of food and feed crops, and the production of pharmaceutical proteins in cereal grains.

Research Groups of the Division

Molecular Cell Biology   
Leader: Ao.Univ.Prof. Dr. Lukas Mach

Plant Cell Walls   
Leader: DI Dr. Georg Seifert

Molecular Plant Biotechnology   
Leader: Ao.Univ.Prof. Dr. Herta Steinkellner

Molecular Plant Physiology and Crop Biotechnology   
Leader: Univ. Prof. Dr. Eva Stoeger

Molecular Plant Glycobiology   
Leader: Assoc. Prof. DI Dr. Richard Strasser

Alternative splicing
Leader: Dr. Maria Kalyna